{"id":14502,"date":"2023-02-24T16:06:06","date_gmt":"2023-02-24T09:06:06","guid":{"rendered":"https:\/\/hpsp-prod.th1.proen.cloud\/%e0%b8%a1%e0%b8%b0%e0%b9%80%e0%b8%a3%e0%b9%87%e0%b8%87%e0%b8%97%e0%b8%b2%e0%b8%87%e0%b9%80%e0%b8%94%e0%b8%b4%e0%b8%99%e0%b8%ad%e0%b8%b2%e0%b8%ab%e0%b8%b2%e0%b8%a3\/"},"modified":"2023-03-06T15:36:58","modified_gmt":"2023-03-06T08:36:58","slug":"esophageal-cancer","status":"publish","type":"post","link":"https:\/\/hpsp.or.th\/en\/esophageal-cancer\/","title":{"rendered":"Esophageal cancer"},"content":{"rendered":"<section class=\"wpb-content-wrapper\"><p>[vc_row content_placement=&#8221;middle&#8221;][vc_column width=&#8221;1\/2&#8243;][vc_column_text]<span style=\"font-weight: 400;\"><strong>Our clinical trial<\/strong>: Esophageal cancer<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Update on 10 February 2022<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Since 2022, we launched the first multi-center randomized trial in Thailand to compare photon therapy or X-ray treatment versus proton therapy in esophageal cancer treatment. Our purpose is to compare two methods of radiation therapy for the treatment of esophageal squamous cell carcinoma (ESCC). The study will compare high-dose intensity-modulated proton therapy (IMPT) with standard-dose intensity-modulated radiation therapy (IMRT). The aim of the trial is to determine if high-dose IMPT is more effective in treating ESCC than standard-dose IMRT. The trial will involve randomly assigning patients with ESCC to either the high-dose IMPT group or the standard-dose IMRT group. The effectiveness of the two treatments will be compared based on factors such as disease control, overall survival, and side effects. The results of this trial will provide important information on the use of IMPT and IMRT in the treatment of ESCC.<\/span>[\/vc_column_text][\/vc_column][vc_column width=&#8221;1\/2&#8243;][vc_single_image image=&#8221;14962&#8243; img_size=&#8221;full&#8221; style=&#8221;vc_box_shadow_border&#8221;][\/vc_column][\/vc_row][vc_row full_width=&#8221;stretch_row&#8221; css=&#8221;.vc_custom_1678088209873{background-color: #eff3fa !important;}&#8221;][vc_column][vc_column_text]<strong>The inclusion criteria include:<\/strong><\/p>\n<ul>\n<li><span style=\"font-weight: 400;\"> Patients with histologically confirmed ESCC<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Age 20-70 years old<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Body weight \u226545 kg<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Good health condition<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Adequate organ function<\/span><\/li>\n<\/ul>\n<p><strong>The exclusion criteria are:<\/strong><\/p>\n<ul>\n<li><span style=\"font-weight: 400;\"> Distant metastasis<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Evidence of tracheoesophageal or esophagobronchial fistula<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Previous or simultaneous cancer within 2 years, except skin cancer<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> History of radiation therapy to the thorax or upper abdomen<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Uncontrolled intercurrent illness<\/span><\/li>\n<li><span style=\"font-weight: 400;\"> Pregnancy or lactation<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">These criteria were established to ensure that patients who are eligible for the study have a similar disease stage and overall health status, and that the results of the trial are as accurate and reliable as possible.<\/span>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column][vc_column_text]<strong>Resource:<\/strong><\/p>\n<p><span style=\"font-weight: 400;\">Oonsiri S, Kitpanit S, Kannarunimit D, Chakkabat C, Lertbutsayanukul C, Prayongrat A. Comparison of intensity modulated proton therapy beam configurations for treating thoracic esophageal cancer. Phys Imaging Radiat Oncol. 2022 Apr 28;22:51-56.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Lertbutsayanukul C, Kitpanit S, Kannarunimit D, Chakkabat C, Oonsiri S, Thephamongkhol K, Puataweepong P, Katanyoo K, Sukhaboon J, Tovanabut C, Chongsathientham S, Treeratsapanich P, Soonthornrak J, Prayongrat A. High-dose Intensity-modulated proton therapy versus Standard-dose Intensity-modulated RadIation therapy for esophageal squamous cell carcinoma (HI-SIRI): study protocol for a randomized controlled clinical trial. Trials. 2022 Oct 22;23(1):897<\/span>[\/vc_column_text][\/vc_column][\/vc_row]<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"<p>[vc_row content_placement=&#8221;middle&#8221;][vc_column width=&#8221;1\/2&#8243;][vc_column_text]Our clinical trial: Esophageal cancer Update on 10 February 2022 Since 2022, we launched the first multi-center randomized trial in Thailand to compare photon therapy or X-ray treatment versus proton therapy in esophageal cancer treatment. Our purpose is to compare two methods of radiation therapy for the treatment of esophageal squamous cell carcinoma<\/p>\n","protected":false},"author":1,"featured_media":14962,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[174],"tags":[],"type_post":[],"class_list":["post-14502","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-research-en"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v20.2.1 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Esophageal cancer - HPSP<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/hpsp.or.th\/en\/esophageal-cancer\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Esophageal cancer - HPSP\" \/>\n<meta property=\"og:description\" content=\"[vc_row content_placement=&#8221;middle&#8221;][vc_column width=&#8221;1\/2&#8243;][vc_column_text]Our clinical trial: Esophageal cancer Update on 10 February 2022 Since 2022, we launched the first multi-center randomized trial in Thailand to compare photon therapy or X-ray treatment versus proton therapy in esophageal cancer treatment. 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